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martes, 28 de julio de 2015

Solicitamos tesista de licenciatura

Solicitamos pasante de licenciatura para realizar tesis en temas relacionados a la Bioseguridad. Ofrecemos amplia capacitación en el tema. Requerimos disponibilidad de horario. Podrá participar en sesiones de entrenamiento relacionados. Informes:  amexbio(arroba)gmail.com

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Emotional motivators might improve hand hygiene among healthcare workers

Campaigns that use feelings such as disgust might help to reduce healthcare associated infection better than rational campaigns that teach infection prevention, writes Layla McCay
Something about articles on hand hygiene in healthcare tempts us to turn the page. Hand hygiene: that bastion of infection control, inspiration for a thousand dog-eared posters proclaiming the critical moments, creator of chapped hands, consumer of time that could otherwise be spent with patients, general guilt inducer.
We know this. We all learnt the importance of hand hygiene back in medical or nursing school. We all sat through the mandatory training and read the hospital policies. We recognise that globally 5-15% of hospital patients acquire a healthcare associated infection during their stay.1 We have seen the studies: healthcare associated infections are being transmitted on the hands of healthcare workers all the time, whether we are measuring blood pressure,2 moving around the patient area,3or handling fluid secretions.4 We know all about hand hygiene.
REFERENCE:
http://www.bmj.com/content/351/bmj.h3968.full?ijkey=sCpSkOxEG2ot4TD&keytype=ref 

lunes, 27 de julio de 2015

Surface-Dried Viruses Can Resist Glucoprotamin-Based Disinfection

Vaccinia virus
Touching of contaminated objects and surfaces is a well-known method of virus transmission. Once they are attached to the hands, viruses can easily get adsorbed and initiate infection. Hence, disinfection of frequently touched surfaces is of major importance to prevent virus spreading. Here we studied the antiviral activity of a glucoprotamin-containing disinfectant against influenza A virus and the model virus vaccinia virus (VACV) dried on inanimate surfaces. The efficacy of the surface disinfectant on stainless steel, polyvinyl chloride, and glass coupons was investigated in a quantitative carrier test. Vacuum-dried viruses were exposed to 0.25%, 0.5%, and 1% disinfectant for 5 min, 15 min, and 30 min without agitation, and residual infectivity was determined by endpoint titration. Although glucoprotamin was highly active against both viruses in suspension, limited antiviral activity against the surface-dried viruses was detected. Even after 30 min of exposure to 1% disinfectant, VACV was not completely inactivated. Furthermore, influenza A virus inactivation was strongly affected by the surface composition during the 5-min and 15-min treatments with 0.25% and 0.5% disinfectant. The results presented in this study highlight the relevance of practical tests to assess the antiviral activity of surface disinfectants. High virucidal activity in solution is not necessarily indicative of high antiviral activity against surface-dried viruses. In addition, we want to emphasize that the mere exposure of surfaces to disinfectants might not be sufficient for virus inactivation and mechanical action should be applied to bring attached viruses into contact with virucidal compounds.

REFERENCE:
Zeitler, Benjamin, and Ingrid Rapp. “Surface-Dried Viruses Can Resist Glucoprotamin-Based Disinfection.” Ed. M. W. Griffiths. Applied and Environmental Microbiology 80.23 (2014): 7169–7175. PMC. Web. 9 July 2015.
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lunes, 20 de julio de 2015

An Evaluation of Antifungal Agents for the Treatment of Fungal Contamination in Indoor Air Environments

Fungal contamination in indoor environments has been associated with adverse health effects for the inhabitants. Remediation of fungal contamination requires removal of the fungi present and modifying the indoor environment to become less favourable to growth.  This may include treatment of indoor environments with an antifungal agent to prevent future growth. However there are limited published data or advice on chemical agents suitable for indoor fungal remediation. The aim of this study was to assess the relative efficacies of five commercially available cleaning agents with published or anecdotal use for indoor fungal remediation. The five agents included two common multi-purpose industrial disinfectants (Cavicide® and Virkon®), 70% ethanol, vinegar (4.0%−4.2% acetic acid), and a plant-derived compound (tea tree (Melaleuca alternifolia) oil) tested in both a liquid and vapour form. Tea tree oil has recently generated interest for its antimicrobial efficacy in clinical settings, but has not been widely employed for fungal remediation. Each antifungal agent was assessed for fungal growth inhibition using a disc diffusion method against a representative species from two common fungal genera, (Aspergillus fumigatus and Penicillium chrysogenum), which were isolated from air samples and are commonly found in indoor air. Tea tree oil demonstrated the greatest inhibitory effect on the growth of both fungi, applied in either a liquid or vapour form. Cavicide® and Virkon® demonstrated similar, although less, growth inhibition of both genera. Vinegar (4.0%–4.2% acetic acid) was found to only inhibit the growth of P. chrysogenum, while 70% ethanol was found to have no inhibitory effect on the growth of either fungi. There was a notable inhibition in sporulation, distinct from growth inhibition after exposure to tea tree oil, Virkon®, Cavicide® and vinegar. Results demonstrate that common cleaning and antifungal agents differ in their capacity to inhibit the growth of fungal genera found in the indoor air environment. The results indicate that tea tree oil was the most effective antifungal agent tested, and may have industrial application for the remediation of fungal contamination in residential and occupational buildings.

Keywords: Airborne fungi, indoor air quality (IAQ), vinegar, tea tree oil, inhibition zone

REFERENCE:
Rogawansamy, Senthaamarai et al. “An Evaluation of Antifungal Agents for the Treatment of Fungal Contamination in Indoor Air Environments.” Ed. William A. Toscano and Paul B. Tchounwou. International Journal of Environmental Research and Public Health 12.6 (2015): 6319–6332. PMC. Web. 9 July 2015.
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jueves, 16 de julio de 2015

Revista Mexicana de Bioseguridad

LA ASOCIACIÓN MEXICANA DE BIOSEGURIDAD A.C.convoca a participar en la:
REVISTA MEXICANA DE BIOSEGURIDAD

Participa con artículos para la difusión digital en nuestra revista sobre los temas relevantes sobre bioseguridad en México, compartiendo sus reflexiones, experiencias y resultados de investigación.
¡ CONOCE NUESTRA REVISTA AQUI !

Mínimo de 3,500 y máximo de 10,000 caracteres (contados sin considerar espacios con la herramienta “número de palabras” en Word).

Tipo de letra: Arial.
Referencias: Para agregar referencias al texto, favor de utilizar el formato de la revista PLOS One.   (http://www.plosone.org/static/guidelines#references)
Adjuntar una o dos fotografías DE SU AUTORÍA (QUE NO SEAN TOMADAS DEL INTERNET) ilustrativas del tema, en buena definición (8megapixeles o superior), con el respectivo texto explicativo que se pondrá al final del artículo.
Adjuntar una fotografía personal reciente con encuadre que abarque de busto a cabeza (medium shot) y un resumen de su Curriculum Vitae.

Enviar el o los textos que propones para publicar, al correo electrónico

revistamexicana(arroba)amexbio.org

Los textos propuestos para publicar serán revisados a la luz de los criterios de publicación.  La determinación de la comisión revisora será comunicada al autor.

ENVÍA ​YA ​TU PARTICIPACIÓN

​Consejo Directivo AMexBio

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lunes, 13 de julio de 2015

Review and Phylogenetic Analysis of qac Genes That Reduce Susceptibility to Quaternary Ammonium Compounds in Staphylococcus Species

The qac genes of Staphylococcus species encode multidrug efflux pumps: membrane proteins that export toxic molecules and thus increase tolerance to a variety of compounds such as disinfecting agents, including quaternary ammonium compounds (for which they are named), intercalating dyes and some antibiotics. In Stapylococcus species, six different plasmid-encoded Qac efflux pumps have been described, and they belong to two major protein families. QacA and QacB are members of the Major Facilitator Superfamily, while QacC, QacG, QacH, and QacJ all belong to the Small Multidrug Resistance (SMR) family. Not all SMR proteins are called Qac and the reverse is also true, which has caused confusion in the literature and in gene annotations. The discovery of qac genes and their presence in various staphylococcal populations is briefly reviewed. A sequence comparison revealed that some of the PCR primers described in the literature for qac detection may miss particular qac genes due to lack of DNA conservation. Despite their resemblance in substrate specificity, the Qac proteins belonging to the two protein families have little in common. QacA and QacB are highly conserved in Staphylococcus species, while qacA was also detected in Enterococcus faecalis, suggesting that these plasmid-born genes have spread across bacterial genera. Nevertheless, these qacA and qacB genes are quite dissimilar to their closest homologues in other organisms. In contrast, SMR-type Qac proteins display considerable sequence variation, despite their short length, even within the Staphylococcus genus. Phylogenetic analysis of these genes identified similarity to a large number of other SMR members, found in staphylococci as well as in other genera. A number of phylogenetic trees of SMR Qac proteins are presented here, starting with genes present in S. aureus and S. epidermidis, and extending this to related genes found in other species of this genus, and finally to genes found in other genera.
Keywords: biocide resistance, MFS, MRSA, phylogeny, qac, S. aureus, smr

REFERENCE:
Wassenaar, Trudy M. et al. “Review and Phylogenetic Analysis of qac Genes That Reduce Susceptibility to Quaternary Ammonium Compounds in Staphylococcus Species.” European Journal of Microbiology & Immunology 5.1 (2015): 44–61. PMC. Web. 30 June 2015.
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jueves, 9 de julio de 2015

Guidelines for the use of cell lines in biomedical research

Cell-line misidentification and contamination with microorganisms, such as mycoplasma, together with instability, both genetic and phenotypic, are among the problems that continue to affect cell culture. Many of these problems are avoidable with the necessary foresight, and these Guidelines have been prepared to provide those new to the field and others engaged in teaching and instruction with the information necessary to increase their awareness of the problems and to enable them to deal with them effectively. The Guidelines cover areas such as development, acquisition, authentication, cryopreservation, transfer of cell lines between laboratories, microbial contamination, characterisation, instability and misidentification. Advice is also given on complying with current legal and ethical requirements when deriving cell lines from human and animal tissues, the selection and maintenance of equipment and how to deal with problems that may arise.

Keywords: cell culture, mycoplasma contamination, Human Tissue Act, cell line, cell line misidentification, cryostorage, Human Tissue Authority, STR profiling, human tissue, Human Fertilisation and Embryology Act

REFERENCE:
Geraghty, R J et al. “Guidelines for the Use of Cell Lines in Biomedical Research.” British Journal of Cancer 111.6 (2014): 1021–1046. PMC. Web. 9 July 2015.
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jueves, 2 de julio de 2015

The race against time (two #ebola vaccines)

The first time Dr Ripley Ballou, Vice President of GlaxoSmithKline (GSK) Biologicals, contacted the World Health Organization (WHO) about a promising Ebola vaccine candidate, it was 24 March 2014 – the day WHO issued news of the Ebola virus disease outbreak in Guinea.
“I was told that since there were no human data, there were no policies or pathways for its use in the current outbreak,” Ballou recalls. ”There was also a strong belief that the usual approach of containments would stop the outbreak.”
When WHO called Ballou a few months later the picture had changed, and on 8 August WHO declared the outbreak a public health emergency of international concern.
“We realized this outbreak was different and the approach used successfully in previous outbreaks – detecting and isolating cases, identifying contacts and safely burying the deceased – was not working,” says Dr Marie-Paule Kieny, WHO Assistant Director-General for Health Systems and Innovation.
Within a month, Kieny and her team hosted a gathering of more than 200 of the world’s leading vaccine experts from industry, academia and regulatory authorities as well as public health officials from the countries affected and experts in filoviruses and viral haemorrhagic diseases.
REFERENCE:
The Race against Time.”
Bulletin of the World Health Organization 93.1 (2015): 7–8. PMC. Web. 24 June 2015.
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lunes, 29 de junio de 2015

Biocontainment of genetically modified organisms by synthetic protein design

Genetically modified organisms (GMOs) are increasingly deployed at large scales and in open environments. Genetic biocontainment strategies are needed to prevent unintended proliferation of GMOs in natural ecosystems. Existing biocontainment methods are insufficient either because they impose evolutionary pressure on the organism to eject the safeguard, because they can be circumvented by environmentally available compounds, or because they can be overcome by horizontal gene transfer (HGT). Here we computationally redesign essential enzymes in the first organism possessing an altered genetic code to confer metabolic dependence on nonstandard amino acids for survival. The resulting GMOs cannot metabolically circumvent their biocontainment mechanisms using environmentally available compounds, and they exhibit unprecedented resistance to evolutionary escape via mutagenesis and HGT. This work provides a foundation for safer GMOs that are isolated from natural ecosystems by reliance on synthetic metabolites.

REFERENCE:
Mandell, Daniel J. et al. “Biocontainment of Genetically Modified Organisms by Synthetic Protein Design.” Nature 518.7537 (2015): 55–60. PMC. Web. 24 June 2015.
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viernes, 26 de junio de 2015

Online Resources for Understanding Outbreaks and Infectious Diseases

Disease outbreaks are hot topics that often receive extensive national and international news coverage, although this coverage may not always be accurate. Engaging students with these current events can be a powerful way to teach about science and health. Accurate disease information is also an important public health issue, as misinformation can lead to fear and poor policy decisions. In this review, we highlight online resources for teaching about outbreaks and infectious diseases that will be useful for scientists and educators working with middle school, high school, and undergraduate students. We particularly focus on current news about infectious diseases, epidemiology, pathogen biology, and vaccines.
Infectious diseases are caused by pathogenic microbes, including viruses, bacteria, and parasites. Some diseases, such as the flu, spread from human to human, while others rely on a vector intermediate—for example, malaria is transmitted by mosquitoes. Outbreaks, or epidemics, are characterized by the rapid spread of disease in a population. An outbreak that becomes global is referred to as a pandemic. In 2009, the global spread of H1N1 “swine” flu was a pandemic, whereas the outbreak of Ebola that began in 2014 is an epidemic in West Africa, not a pandemic.
REFERENCE:
Barber, Nicola C., and Louisa A. Stark. “Online Resources for Understanding Outbreaks 
and Infectious Diseases.” CBE Life Sciences Education 14.1 (2015): fe1. PMC. Web. 24 June 2015.
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jueves, 25 de junio de 2015

Convocatoria para el conformar el Consejo Consultivo Científico de Sanidad Vegetal, Biología Molecular de Animales y Biotecnología en Alimentos

Por considerar que pudiera ser de su interés, les informo que se encuentra abierta la Convocatoria 2015 para formar parte del Consejo Consultivo Científico en las disciplinas de Sanidad Vegetal, Biología Molecular de Animales y Biotecnología en Alimentos hasta el  31 de julio de 2015.  Para mayor información, los invito a consultar las bases en nuestra página electrónica: CONACYT
Asimismo, agradeceremos su valioso apoyo para distribuir esta información entre aquellas personas que consideren pudieran estar interesadas y estimen pertinente.
Saludos cordiales,
Dra. Natalhie Campos 
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miércoles, 24 de junio de 2015

Survival of Enveloped and Non-Enveloped Viruses on Inanimate Surfaces

Abstract
In the present study, we evaluated the viability of non-enveloped viruses, minute virus of mice (MVM) and coxsackievirus B4 (CVB4), and enveloped-viruses, influenza A virus (H1N1) and herpes simplex virus type 1 (HSV-1), on surfaces. We also investigated the impact of the initial concentration of proteins and sodium chloride on the persistence of infectious CVB4 on surfaces. Viral suspensions (>104.5 TCID50) were applied to petri dish lids and dried under the air flow of a biosafety cabinet. The recovered viral preparations were titered on appropriate cell lines. Enveloped viruses persisted for less than 5 days while CVB4 and MVM persisted for weeks. However, repetitive cycles of drying and resuspension had a stronger virucidal effect on CVB4 than on H1N1 and HSV-1. These repetitive cycles had no effect on the infectious titer of MVM. When exposed to drying, the initial concentrations of bovine serum albumin (from 0 to 90 mg mL−1), fetal calf serum (from 0 to 100%), and sodium chloride (from 0 to 300 mg mL−1) affected the viability of CVB4. CVB4 was more likely to be inactivated by drying in a protein-rich medium, whereas the impact of drying was reduced in the presence of sodium chloride. The results of the present study demonstrated that the resistance of viruses to drying, as suggested by iterative drying, was not due to the heterogeneity of viral subpopulations, but was influenced by media compositions and component concentrations, as illustrated in the model of CVB4.
Keywords: coxsackievirus B4, influenza A virus, minute virus of mice, herpes simplex type 1, persistence
REFERENCE:
Firquet, Swan et al. “Survival of Enveloped and Non-Enveloped Viruses on Inanimate Surfaces.” Microbes and Environments 30.2 (2015): 140–144. PMC. Web. 24 June 2015.



martes, 23 de junio de 2015

Fotos del 7º SIBB 2015 #AMexBio

En el siguiente link podrán ver las fotos del 7º Simposio de Bioseguridad y Biocustodia.
>> FOTOS EN FACEBOOK <<


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sábado, 20 de junio de 2015

Cold Air Plasma To Decontaminate Inanimate Surfaces of the Hospital Environment

The hospital environment harbors bacteria that may cause health care-associated infections. Microorganisms, such as multiresistant bacteria, can spread around the patient's inanimate environment. Some recently introduced biodecontamination approaches in hospitals have significant limitations due to the toxic nature of the gases and the length of time required for aeration. This study evaluated the in vitrouse of cold air plasma as an efficient alternative to traditional methods of biodecontamination of hospital surfaces. Cultures of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli, and Acinetobacter baumannii were applied to different materials similar to those found in the hospital environment. Artificially contaminated sections of marmoleum, mattress, polypropylene, powder-coated mild steel, and stainless steel were then exposed to a cold air pressure plasma single jet for 30 s, 60 s, and 90 s, operating at approximately 25 W and 12 liters/min flow rate. Direct plasma exposure successfully reduced the bacterial load by log 3 for MRSA, log 2.7 for VRE, log 2 for ESBL-producing E. coli, and log 1.7 for A. baumannii. The present report confirms the efficient antibacterial activity of a cold air plasma single-jet plume on nosocomial bacterially contaminated surfaces over a short period of time and highlights its potential for routine biodecontamination in the clinical environment.
Reference:
Cahill, Orla J. et al. “Cold Air Plasma To Decontaminate Inanimate Surfaces of the Hospital Environment.” Ed. C. A. Elkins. Applied and Environmental Microbiology 80.6 (2014): 2004–2010. PMC. Web. 20 June 2015.
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jueves, 21 de mayo de 2015

Examen de certificación de profesionales en bioseguridad

F
English version,  scroll down
Publicado el 7/Mayo/2015

 
Asegura tu lugar. 
Inscríbete antes del 25 de Mayo!

La Asociación Mexicana de Bioseguridad (AMEXBIO) se complace en colaborar con la Federación Internacional de Asociaciones de Bioseguridad (IFBA) en la aplicación de su Examen para la Certificación Profesional en Gestión de Riesgo Biológico durante nuestra próxima conferencia de junio de 2015. Más detalles sobre el 7o Simposio Internacional de Bioseguridad y Biocustodia de AMEXBIO se pueden encontrar en http://www.amexbio.wildapricot.org/SIBB
La certificación profesional de la IFBA identifica a individuos con competencias demostradas en los principios y prácticas fundamentales en la gestión de riesgos biológicos. Esta es una gran oportunidad para que nuestros colegas puedan avanzar en su carrera y lograr reconocimiento internacional. Más detalles sobre el programa de certificación se pueden encontrar aquí. Pueden presentar el examen personas de cualquier país que cumplan los requisitos y se registren en línea. 
Las preguntas del examen y todos sus materiales están en idioma Inglés. El examen se llevará a cabo el sábado 06 de junio de 2015 de 7-9 am en el aula UNAM1 del Instituto Nacional de Enfermedades Respiratorias en la Ciudad de México. El examen requiere de registro previo. Todas las solicitudes deben ser ingresadas a través del sistema Certifior en https://ifba.certifior.com. En estas instrucciones (PDF) se explica el proceso de solicitud. Para obtener información sobre la guía de estudio, el contenido del examen y el tipo de preguntas, haga clic aquí (PDF). 

Los usuarios de computadoras Mac, se recomienda utilizar navegador Chrome o Firefox durante el registro.
 Los usuarios de computadoras Mac, se recomienda utilizar navegador Chrome o Firefox durante el registro.
Para más información y consultas sobre esta sesión por favor póngase en contacto (en inglés) con la Secretaría de IFBA por correo electrónico a secretariat@internationalbiosafety.org.

ENGLISH
The Mexican Biosafety Association (AMEXBIO) is pleased to collaborate with the International Federation of Biosafety Associations in the delivery of the IFBA’s Professional Certification in Biorisk Management examination during our upcoming June conference. Further details on the AMEXBIO’s 7th International Symposium can be found at http://www.amexbio.wildapricot.org/SIBB  
The IFBA’s professional certification identifies individuals with demonstrated competencies in the fundamental principles & practices of biorisk management. This is an exciting opportunity for our members to advance their careers and achieve international recognition among colleagues. Further details on the certification program can be found here.
The exam questions and all its materials are in English language. The exam session will be held on Saturday June 6th from 7:00am to 9:00am in Room UNAM1 at the National Institute of Respiratory Disease in Mexico City. All applications must be processed through the on-line Certifior system at https://ifba.certifior.com. These instructions(PDF) will guide individuals through the application process. For information on the exam content and sample questions, click here(PDF).  

For further details and enquiries on this session please contact the IFBA Secretariat by email at secretariat@internationalbiosafety.org.

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miércoles, 20 de mayo de 2015

Avisos generales sobre el Simposio de Bioseguridad

Acercándose la fecha del 7º Simposio de Bioseguridad y Biocustodia, la AMexBio desea realizar algunos avisos generales para que disfruten mejor sus actividades durante el mismo y tengan el menor número de inconvenientes:
  1. REGISTRO: La fecha límite para el registro en línea es el día 27 de Mayo de 2015. Las personas que después de esa fecha deseen registrarse tendrán que realizar el pago-depósito en el banco, y entregar la ficha de depósito en el evento. POR SEGURIDAD, NO SE RECIBEN PAGOS EN EFECTIVO DURANTE EL SIMPOSIO. Vean esa información AQUI. Por favor lleguen con anticipación para realizar el trámite de registro y gafetes. Para ver los costos de los eventos visiten la siguiente PÁGINA.
  2. FACTURACIÓNTodas las facturas se realizan dentro del mes que se realiza el pago. Por favor, no olviden llevar la información fiscal completa (dirección, RFC), para emitirles la factura durante el simposio. AMexBio regularmente no envía documentación por correo normal o mensajería.
  3. AULASTodos los cursos y eventos se realizarán dentro de las Instalaciones del INER. Las aulas de la UNAM a las que hace referencia el programa se encuentran dentro del INER,
  4. ESTACIONAMIENTOSEl INER no cuenta con estacionamiento para el público en general. Recomendamos usar los estacionamientos que se encuentran en las inmediaciones del INER. Por favor revisen el mapa de la sede, con las direcciones para que los localicen. El robo de coches o autopartes en la vía pública es un problema en toda la Cd. de México. Estacionamiento 1: Calle Sillón de Mendoza No. 24. Col. Toriella Guerra. Costo: $ 50.00 x día. Estacionamiento 2: Chimalcoyotl No. 13. Col. Tlalpan. Costo: $ 35.00 x día.
  5. HOTELLas personas que se hospeden en el "Hotel Holiday Inn & Suites Médica Sur", que se encuentra a algunas cuadras del INER. Dirección: Puente De Piedra : 150 Col. Toriello Guerra México 14050Dentro del Hospital Médica SurTorre 3, 5º Piso. Entrada por estacionamiento techado.
  6. Lleguen con anticipación, 15 a 20 minutos mínimo, por que las distancias a caminar son largas.
http://www.amexbio.wildapricot.org/Sede/

MAPA SEDE
https://www.google.com/maps/d/edit?mid=zMDDWQr8qUh4.k4yiOudOubwI&usp=sharing

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jueves, 7 de mayo de 2015

Membresías AMEXBIO 2015


Publicado en Diciembre 2014. Modificada Marzo 2015.
Para apoyar el cumplimiento de los objetivos de la Asociación Mexicana de Bioseguirdad A.C. se está llevando a cabo la campaña de renovación y actualización de membresía 2014 - 2015, la cual nos permitirá desarrollar distintos proyectos como asambleas, simposio, cursos en línea, seminarios, talleres, y otorgar un mayor número de becas para los asistentes. Una de las fuentes de ingreso de AMEXBIO son las aportaciones de los miembros, por lo que invitamos a actualizar su membresía o unirse como miembro activo.

Los BENEFICIOS que obtendrás al pagar tu membresía de 2015 son:
  1. Cuotas preferenciales para el Simposio Anual, cursos en línea, eventos, seminarios y productos que organice y promueva AMEXBIO.
  2. Accesos a la biblioteca de videos y cursos en nuestro portal de Formación Académica, a través de clave personalizada que te llegará al pagar tu membresía.
  3. Poder conocer las diferentes convocatorias de las instituciones que apoyan con recursos o descuentos para participar en eventos nacionales e internacionales sobre temas de bioseguridad.
  4. Contar con su perfil académico y poder participar como profesor en nuestros cursos en línea o cursos presenciales.
  5. Participar activamente en todos los eventos académicos que organice nuestra Asociación.
  6. Constancia de miembro activo.
Para lograr este objetivo, aprovecha el “Plan 2015 AMEXBIO” que consiste en:

A partir de 01-Febrero-2015, el costo de la Membresía se incrementó a $900.- MXN.
  1. Nuevos miembros. Si no eres miembro (Estatus visitante o en blanco): Los profesores o investigadores de nuevo ingreso deberán enviar el pago de $ 900.00, y actualizar su perfil en la página de miembros: www.amexbio.wildapricot.org y enviar la documentación solicitada, al correo electrónico de tesoreria(arroba)amexbio.org. Por favor revisen la convocatoria en: http://amexbio.org/docs/convocatoriaM.pdf
  2. Renovaciones miembros activos.  Si ya eres miembro y estas al corriente (Estatus Active): A partir del 01 de Febrero de 2015, incrementa a $ 900.- MXN
  3. Renovaciones vencidas, pagos pendientes. Si ya eres miembro pero no estás al corriente (Estatus Pending Renewal o Lapsed):  $ 900.- MXN
Las solicitudes nuevas se reciben de ENERO a MAYO de cada año!

Depósito bancario a nombre de:Cliente: ASOCIACION MEXICANA DE BIOSEGURIDAD A.C.
Banco: BANAMEX
CLABE interbancaria: 002180024179950244
Sucursal: 0241
Cuenta: 7995024
Referencia: (nombre del miembro)
Enviar el comprobante de depósito escaneado y datos de facturación (si es necesario) y en el caso de nuevo ingreso, los documentos solicitados, al siguiente correo electrónico: tesoreria(arroba)amexbio.org. Se emitirá la factura correspondiente, la emisión de la clave de acceso para el portal de Formación Académica, así como la constancia de membresía, que se enviarán por correo electrónico.

Por favor ayúdanos a distribuir esta información entre tus contactos que les pueda interesar en participar en AMEXBIO.

Atentamente

Dr. José Luis Sandoval.
Presidente
Consejo Directivo AMEXBIO

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7º Simposio Internacional de Bioseguridad y Biocustodia #SIBB15

DESCARGAR
Publicado el 17/Feb/2015
En su 7a. edición, el Simposio Internacional de Bioseguridad y Biocustodia 2015 (#SIBB15), la Asociación Mexicana de Bioseguridad A.C. en colaboración con el Instituto Nacional de Enfermedades Respiratorias se realizará del 3 al 6 de Junio de 2015. En este VII Simposio se presentan un programa de cursos presimposio, pláticas magistrales, mesas de discusión, seminarios y exposición comercial que congregarán a expertos e interesados de México y el extranjero.

¿Quién debe asistir?

Profesionales de la salud humana, ámbito agropecuario e industrial involucrados en temas de bioseguridad, biocontención, gestión de riesgos biológicos y biotecnológicos, involucrados en manejo de materiales biológico infecciosos. Este simposio de bioseguridad (SIBB) es una reunión especializada en el entrenamiento, análisis, discusión y planteamiento de propuestas alrededor de la seguridad biológica y los materiales biológico infecciosos en México y nuestro entorno. El SIBB es organizado por la Asociación Mexicana de Bioseguridad A.C. desde 2009. 

Por favor consulten toda la información en la Página del VII Simposio
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lunes, 4 de mayo de 2015

Nitrile versus Latex for Glove Juice Sampling

The objective of this study was to explore the utility of nitrile gloves as a replacement for latex surgical gloves in recovering bacteria from the hands. Two types of nitrile gloves were compared to latex gloves using the parallel streak method. Streaks of Klebsiella pneumoniae and Staphylococcus aureus were made on tryptic soy agar plates, and the zones of inhibition were measured around pieces of glove material placed on the plates. Latex gloves produced a mean zone of inhibition of 0.28 mm, compared to 0.002 mm for nitrile gloves (p<.001). While the parallel streak method is not intended as a quantitative estimate of antimicrobial properties, these results suggest that nitrile may be a viable alternative to latex in glove juice sampling methods, since nitrile avoids the risk of latex exposure.

REFERENCIA
Landers TF, Dent A. Nitrile versus Latex for Glove Juice Sampling. PLoS One. 2014 Oct 15;9(10):e110686.
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lunes, 27 de abril de 2015

REVIEW: Outbreaks Associated with Contaminated Antiseptics and Disinfectants

Multiple nosocomial outbreaks have resulted from inadequate antisepsis or disinfection. Inadequate skin antisepsis may result from a lack of intrinsic antimicrobial activity of the antiseptic, a resistant pathogen, overdilution of the antiseptic, or the use of a contaminated antiseptic. The inadequate disinfection of medical devices or environmental surfaces may result from a lack of intrinsic antimicrobial activity of the disinfectant, an incorrect choice of a disinfectant, a resistant pathogen, overdilution of the disinfectant, an inadequate duration of disinfection, a lack of contact between the disinfectant and the microbes, or the use of a contaminated disinfectant. Editorials have noted that contaminated antiseptics and disinfectants have been the occasional vehicles of hospital infections for more than 50 years. This paper concisely reviews nosocomial outbreaks associated with the use of a microbiologically contaminated germicide and focuses on the currently recommended germicides.

REFERENCIA:
Weber D.J. et al. Outbreaks Associated with Contaminated Antiseptics and Disinfectants. Antimicrob. Agents Chemother. December 2007 vol. 51 no. 12 4217-4224
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lunes, 13 de abril de 2015

Evaluating Environmental Persistence and Disinfection of the #Ebola Virus Makona Variant.

Background: The current disease outbreak caused by the Ebola virus Makona variant (EBOV/Mak) has led to unprecedented morbidity and lethality given its geographic reach and sustained transmission. Sodium hypochlorite and ethanol are well-accepted decontamination agents, however little published evidence supports the selection of appropriate concentrations and contact times. The present study addresses the environmental robustness of EBOV/Mak and evaluates the effectiveness of sodium hypochlorite and ethanol as disinfectants.
Methods: EBOV/Mak was suspended in a simulated organic soil load and dried onto surfaces. Viability was measured at 1 hour, 24 hours, 72 hours, and 192 hours. For the evaluation of disinfectants, EBOV/Mak in a simulated organic soil was dried onto stainless steel carriers and disinfected with 0.01% (v/v), 0.1% (v/v), 0.5% (v/v) and 1% (v/v) sodium hypochlorite solutions or 67% (v/v) ethanol at contact times of 1, 5 or 10 minutes.
Results: EBOV/Mak persisted longer on steel and plastic surfaces (192 hours) than cotton (<24 hours). Dilute sodium hypochlorite (0.01% and 0.1%) showed little antiviral action, whereas 0.5% and 1% sodium hypochlorite solutions demonstrated recoverable virus at one minute but sterilized surfaces in five minutes. Disinfection with 67% ethanol did not fully clear infectious virions from 3/9 carriers at 1 minute but sterilized all carriers at 5 and 10 minutes.
Conclusions: Sodium hypochlorite and ethanol effectively decontaminate EBOV/Mak suspended in a simulated organic load; however, selection of concentration and contact time proves critical.

REFERENCIA:
Cook BWM, et al. Evaluating Environmental Persistence and Disinfection of the Ebola Virus Makona VariantViruses. 2015; 7(4):1975-1986.
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Biorisk management: Laboratory biosecurity guidance #WHO


The present document aims to expand the laboratory biosecurity concepts introduced in Laboratory Safety Manual 2004 (LBM3), and to strike a balance between the long-known biosafety procedures and practices described in LBM3 and the more recently introduced and broader biosecurity concepts. It further introduces the overarching "biorisk management" approach that has resulted from careful thinking, comprehensive study of prevailing practices and recommendations, review of international norms and standards, and relevant ethical considerations Shortcomings currently observed in a number of settings are discussed, and practical solutions are proposed.
The document is intended for the use of relevant national regulatory authorities, laboratory directors (laboratory managers) and laboratory workers, all of whom play key roles in the field of biosciences and in public health in general. 

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Manual de #bioseguridad en el laboratorio de #tuberculosis

Laboratory biosafety is the process of applying a combination of administrative controls, containment principles, practices and procedures, safety equipment, emergency preparedness, and facilities to enable laboratory staff to work safely with potentially infectious microorganisms; biosafety also aims at preventing unintentional exposure to pathogens or their accidental release. This manual describes the minimum biosafety measures that should be implemented at the different levels of tuberculosis (TB) testing laboratories to reduce the risk of a laboratory-acquired infection.

MANUAL EN ESPAÑOL
ENGLISH MANUAL
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jueves, 2 de abril de 2015

BSL-3 Laboratory User Training Program at NUITM-KEMRI

Pathogens handled in a Biosafety Level 3 (BSL-3) containment laboratory pose significant risks to laboratory staff and the environment. It is therefore necessary to develop competency and proficiency among laboratory workers and to promote appropriate behavior and practices that enhance safety through biosafety training. Following the installation of our BSL-3 laboratory at the Center for Microbiology Research-Kenya Medical Research Institute in 2006, a biosafety training program was developed to provide training on BSL-3 safety practices and procedures. The training program was developed based on World Health Organization specifications, with adjustments to fit our research activities and biosafety needs. The program is composed of three phases, namely initial assessment, a training phase including theory and a practicum, and a final assessment. This article reports the content of our training program.
REFERENCE:
Bundi M, et al. BSL-3 Laboratory User Training Program at NUITM-KEMRI. Trop Med Health. 2014 Dec;42(4):171-6.
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