Úneta a la lista de correo. Requiere aprobación
Correo electrónico:
Consultar este grupo

lunes, 2 de mayo de 2016

Respiratory consequences of N95-type Mask usage in pregnant healthcare workers-a controlled clinical study.

Tight fitting Hans Rudolph respirator masks
used in Phase II. (
a) Control cycles with outlet
open to air, and (
b) N95 cycles with outlet
covered by N95 mask materials
BACKGROUND: Outbreaks of emerging infectious diseases have led to guidelines recommending the routine use of N95 respirators for healthcare workers, many of whom are women of childbearing age. The respiratory effects of prolonged respirator use on pregnant women are unclear although there has been no definite evidence of harm from past use.
METHODS: We conducted a two-phase controlled clinical study on healthy pregnant women between 27 to 32 weeks gestation. In phase I, energy expenditure corresponding to the workload of routine nursing tasks was determined. In phase II, pulmonary function of 20 subjects was measured whilst at rest and exercising to the predetermined workload while breathing ambient air first, then breathing through N95-mask materials.
RESULTS: Exercising at 3 MET while breathing through N95-mask materials reduced mean tidal volume (TV) by 23.0 % (95 % CI -33.5 % to -10.5 %, p < 0.001) and lowered minute ventilation (VE) by 25.8 % (95 % CI -34.2 % to -15.8 %, p < 0.001), with no significant change in breathing frequency compared to breathing ambient air. Volumes of oxygen consumption (VO2) and carbon dioxide expired (VCO2) were also significantly reduced; VO2 by 13.8 % (95 % CI -24.2 % to -3 %, p = 0.013) and VCO2 by 17.7 %, (95 % CI -28.1 % to -8.6 %, p = 0.001). Although no changes in the inspired oxygen and carbon dioxide concentrations were demonstrated, breathing through N95-mask materials during low intensity work (3 MET) reduced expired oxygen concentration by 3.2 % (95 % CI: -4.1 % to -2.2 %, p < 0.001), and increased expired carbon dioxide by 8.9 % (95 % CI: 6.9 % to 13.1 %; p <0.001) suggesting an increase in metabolism. There were however no changes in the maternal and fetal heart rates, finger-tip capillary lactate levels and oxygen saturation and rating of perceived exertion at the work intensity investigated.
CONCLUSIONS: Breathing through N95 mask materials have been shown to impede gaseous exchange and impose an additional workload on the metabolic system of pregnant healthcare workers, and this needs to be taken into consideration in guidelines for respirator use. The benefits of using N95 mask to prevent serious emerging infectious diseases should be weighed against potential respiratory consequences associated with extended N95 respirator usage.

REFERENCE:
Tong PS, et al. Respiratory consequences of N95-type Mask usage in pregnant healthcare workers-a controlled clinical study. Antimicrob Resist Infect Control. 2015 Nov 16;4:48. doi: 10.1186/s13756-015-0086-z. eCollection 2015.

-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

martes, 26 de abril de 2016

Examen de certificación en gestión de riesgo #IFBA

English version,  scroll down
Asegura tu lugar.  
Inscríbete antes del 8 DE JUNIO!
La Asociación Mexicana de Bioseguridad (AMEXBIO) se complace en colaborar con la Federación Internacional de Asociaciones de Bioseguridad (IFBA) en la aplicación de su Examen para la Certificación Profesional en Gestión de Riesgo Biológico durante nuestra próxima conferencia de junio de 2016. Además de ofrecer la Certificación Profesional en Gestión de Riesgos Biológicos, también vamos a ofrecer la nueva Certificación Profesional en Gestión de Residuos Biológicos. Tenga en cuenta que sólo aquellos que han completado con éxito la certificación en Gestión de Riesgos Biológicos son elegibles para esta nueva certificación.
Más detalles sobre el 8º Simposio Internacional de Bioseguridad y Biocustodia de AMEXBIO se pueden encontrar en http://www.amexbio.wildapricot.org/SIBB
La certificación profesional de la IFBA identifica a individuos con competencias demostradas en los principios y prácticas fundamentales en la gestión de riesgos biológicos. Esta es una gran oportunidad para que nuestros colegas puedan avanzar en su carrera y lograr reconocimiento internacional.
Más detalles sobre el programa de certificación se pueden encontrar AQUI. Pueden presentar el examen personas de cualquier país que cumplan los requisitos y se registren en línea. Las preguntas del examen y todos sus materiales están en idioma Inglés. La sesión de examen se llevará a cabo el jueves 16 de junio a las 2:00 pm en el segundo piso Sala de reuniones, Instituto de Diagnóstico y Referencia Epidemiológicos (INDRE) en la Ciudad de México. El examen requiere de registro previo. Todas las solicitudes deben ser ingresadas a través del sistema Certifior en https://ifba.certifior.com. En estas INSTRUCCIONES se explica el proceso de solicitud. Para obtener información sobre la guía de estudio, el contenido del examen y el tipo de preguntas, haga clic GUIA DE ESTUDIO 

Los usuarios de computadoras Mac, se recomienda utilizar navegador Chrome o Firefox durante el registro.
.
Para más información y consultas sobre esta sesión por favor póngase en contacto (en inglés) con la Secretaría de IFBA por correo electrónico a: secretariat@internationalbiosafety.org.
------------------------------------------------------------
ENGLISH
The Mexican Biosafety Association (AMEXBIO) is pleased to collaborate with the International Federation of Biosafety Associations in the delivery of the IFBA’s Professional Certification in Biorisk Management examination during our upcoming June conference. Further details on the AMEXBIO’s 7th International Symposium can be found at http://www.amexbio.wildapricot.org/SIBB  
The IFBA’s professional certification identifies individuals with demonstrated competencies in the fundamental principles & practices of biorisk management. This is an exciting opportunity for our members to advance their careers and achieve international recognition among colleagues. Further details on the certification program can be found HERE.
The exam questions and all its materials are in English language. The exam session will be held on Saturday June 16 at the Instituto de Diagnóstico y Referencia Epidemiológica in Mexico City. All applications must be processed through the on-line Certifior system at https://ifba.certifior.comThese instructions will guide individuals through the application process. For information on the exam content and sample questions, click here.  

For further details and enquiries on this session please contact the IFBA Secretariat by email at secretariat@internationalbiosafety.org.


-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

lunes, 25 de abril de 2016

Semana de Vacunación en las Américas, Abril 23 - 30, 2016 #vacúnate

¡Te invitamos a celebrar la SVA 2016 este año para alcanzar el oro a través de la vacunación! El 14º aniversario de la Semana de Vacunación en las Américas se celebrará del 23 al 30 de abril del 2016, con el eslogan regional: “¡Vamos por el oro! ¡Vacúnate!” Las vacunas son patógenos debilitados o muertos que ayudan a tu sistema inmune a combatir enfermedades.Las vacunas no hacen que te enfermes, pero preparan tu cuerpo para luchar contra la enfermedad si te expones a los patógenos en el futuro. Las vacunas refuerzan tu sistema inmune y te ayudan a combatir más de 20 enfermedades prevenibles diferentes.


-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

sábado, 23 de abril de 2016

SEMINARIO INTERNACIONAL

SEMINARIO INTERNACIONAL

Regulación de la protección
De los trabajadores de la salud


Viernes 20 de mayo de 2016, 9:00 hrs. Dirigido a todo público interesado. 
Cupo limitado a la capacidad de la sede. 
Acceso gratuito.

Instituto de Investigaciones Jurídicas, UNAM, Ciudad de México.


Para ver UBICACIÓN DEL INSTITUTO y formas de acceder a él, pulse el siguiente vínculo: http://www.juridicas.unam.mx/inst/ubicacion/
Circuito Maestro Mario de la Cueva s/n, Ciudad de la Investigación en Humanidades, 
Ciudad Universitaria, Delegación Coyoacán, C.P. 04510, México, D. F.

----------------------------------------------------------- Sigue este Blog en Facebook y Twitter https://www.facebook.com/seguridadbiologica www.twitter.com/klintsy

jueves, 21 de abril de 2016

Randomised Trial of Cloth Masks Compared with Medical Masks in Healthcare Workers

Objective: The aim of this study was to compare the efficacy of cloth masks to medical masks in hospital healthcare workers (HCWs). The null hypothesis is that there is no difference between medical masks and cloth masks.
Setting: 14 secondary-level/tertiary-level hospitals in Hanoi, Vietnam.
Participants: 1607 hospital HCWs aged ≥18 years working full-time in selected high-risk wards.
Intervention: Hospital wards were randomised to: medical masks, cloth masks or a control group (usual practice, which included mask wearing). Participants used the mask on every shift for 4 consecutive weeks.
Main outcome measure: Clinical respiratory illness (CRI), influenza-like illness (ILI) and laboratory-confirmed respiratory virus infection.
Results: The rates of all infection outcomes were highest in the cloth mask arm, with the rate of ILI statistically significantly higher in the cloth mask arm (relative risk (RR)=13.00, 95% CI 1.69 to 100.07) compared with the medical mask arm. Cloth masks also had significantly higher rates of ILI compared with the control arm. An analysis by mask use showed ILI (RR=6.64, 95% CI 1.45 to 28.65) and laboratory-confirmed virus (RR=1.72, 95% CI 1.01 to 2.94) were significantly higher in the cloth masks group compared with the medical masks group. Penetration of cloth masks by particles was almost 97% and medical masks 44%.
Conclusions: This study is the first RCT of cloth masks, and the results caution against the use of cloth masks. This is an important finding to inform occupational health and safety. Moisture retention, reuse of cloth masks and poor filtration may result in increased risk of infection. Further research is needed to inform the widespread use of cloth masks globally. However, as a precautionary measure, cloth masks should not be recommended for HCWs, particularly in high-risk situations, and guidelines need to be updated.

Strengths and limitations of this study:

  1. The use of cloth masks is widespread around the world, particularly in countries at high-risk for emerging infections, but there have been no efficacy studies to underpin their use.
  2. This study is large, a prospective randomised clinical trial (RCT) and the first RCT ever conducted of cloth masks.
  3. The use of cloth masks are not addressed in most guidelines for health care workers—this study provides data to update guidelines.
  4. The control arm was ‘standard practice’, which comprised mask use in a high proportion of participants. As such (without a no-mask control), the finding of a much higher rate of infection in the cloth mask arm could be interpreted as harm caused by cloth masks, efficacy of medical masks, or most likely a combination of both.

REFERENCE:
MacIntyre, CR et al. “A Cluster Randomised Trial of Cloth Masks Compared with Medical Masks in Healthcare Workers.” BMJ Open 5.4 (2015): e006577. PMC. Web. 16 Apr. 2016.

-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

lunes, 18 de abril de 2016

Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals



Contact agar plate cultures showing bacterial colonies
recovered from a patient’s overbed table before (
left)
and after (
right) the surface was cleaned by a housekeeper
using contaminated quaternary ammonium disinfectant.
Colonies on right are 
Serratia marcescens andAchromobacter xylosoxidans
Experts agree that careful cleaning and disinfection of environmental surfaces are essential elements of effective infection prevention programs. However, traditional manual cleaning and disinfection practices in hospitals are often suboptimal. This is often due in part to a variety of personnel issues that many Environmental Services departments encounter. Failure to follow manufacturer's recommendations for disinfectant use and lack of antimicrobial activity of some disinfectants against healthcare-associated pathogens may also affect the efficacy of disinfection practices. Improved hydrogen peroxide-based liquid surface disinfectants and a combination product containing peracetic acid and hydrogen peroxide are effective alternatives to disinfectants currently in widespread use, and electrolyzed water (hypochlorous acid) and cold atmospheric pressure plasma show potential for use in hospitals. Creating "self-disinfecting" surfaces by coating medical equipment with metals such as copper or silver, or applying liquid compounds that have persistent antimicrobial activity surfaces are additional strategies that require further investigation. Newer "no-touch" (automated) decontamination technologies include aerosol and vaporized hydrogen peroxide, mobile devices that emit continuous ultraviolet (UV-C) light, a pulsed-xenon UV light system, and use of high-intensity narrow-spectrum (405 nm) light. These "no-touch" technologies have been shown to reduce bacterial contamination of surfaces. A micro-condensation hydrogen peroxide system has been associated in multiple studies with reductions in healthcare-associated colonization or infection, while there is more limited evidence of infection reduction by the pulsed-xenon system. A recently completed prospective, randomized controlled trial of continuous UV-C light should help determine the extent to which this technology can reduce healthcare-associated colonization and infections. In conclusion, continued efforts to improve traditional manual disinfection of surfaces are needed. In addition, Environmental Services departments should consider the use of newer disinfectants and no-touch decontamination technologies to improve disinfection of surfaces in healthcare.

REFERENCE:
Boyce JM. Modern technologies for improving cleaning and disinfection of environmental surfaces in hospitals. Antimicrob Resist Infect Control. 2016 Apr 11;5:10. doi: 10.1186/s13756-016-0111-x. eCollection 2016. Review.
----------------------------------------------------------- 
Sigue este Blog en Facebook y Twitter

jueves, 31 de marzo de 2016

Microbial aerosol liberation from soiled textiles isolated during routine residuals handling in a modern health care setting

BACKGROUND: A wide variety of specialty textiles are used in health care settings for bedding, clothing, and privacy. The ability of textiles to host or otherwise sequester microbes has been well documented; however, their reciprocal potential for liberating airborne bacteria remains poorly characterized. In response, a multi-season survey of bacterial bioaerosols was conducted in the origin and terminus of residual paths which are specifically designed to isolate soiled hospital textiles as they are moved to laundering. This survey used conventional optical particle counting which incorporated multi-channel fluorescence in conjunction with molecular phylogenetic analyses to characterize the bioaerosols liberated during soiled textile storage--immediately before and after the occupation of a modern hospital. Although outfitted with a HEPA filtration system, the number of airborne particles presenting fluorescing optical signatures consistent with airborne bacteria and fungi significantly increased in textile holding rooms soon after the hospital's commissioning, even though these isolated residual areas rarely host personnel. The bioaerosol liberated during textile storage was characterized using Illumina MiSeq sequencing of bacterial 16S ribosomal ribonucleic acid (rRNA) genes. Gene copies recovered by quantitative PCR from aerosol collected in co-located impingers were consistent with fluorescence gated optical particle counting.
RESULTS: The relative abundance patterns of proximal bacterial bioaerosol were such that the air in the origin and terminus of textile storage rooms could not be differentiated once the hospital began processing soiled linens. Genes from microbes typically associating with human skin, feces, and hair--Staphylococcus, Propionibacteria, Corynebacteria, Lactobacillus, and Streptococcus spp.--dominated the aerosol abundance profiles in textile holding rooms, which were generally far less diverse than communities recovered from surfaces in patient rooms.
CONCLUSIONS: These results suggest that aerosol partitioning from the routine handling of soiled textiles can contribute to airborne exposures in the health care environment.
REFERENCE:
Handorean A, et al. Microbial aerosol liberation from soiled textiles isolated during routine residuals handling in a modern health care setting. Microbiome. 2015 Dec 9;3:72. doi: 10.1186/s40168-015-0132-3.

-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

lunes, 28 de marzo de 2016

Effects of Disinfectants on Larval Development of #Ascaris suum Eggs

Ascaris suum eggs in various conditions. 
The objective of this study was to evaluate the effects of several different commercial disinfectants on the embryogenic development of Ascaris suum eggs. A 1-ml aliquot of each disinfectant was mixed with approximately 40,000 decorticated or intact A. suum eggs in sterile tubes. After each treatment time (at 0.5, 1, 5, 10, 30, and 60 min), disinfectants were washed away, and egg suspensions were incubated at 25˚C in distilled water for development of larvae inside. At 3 weeks of incubation after exposure, ethanol, methanol, and chlorohexidin treatments did not affect the larval development of A. suum eggs, regardless of their concentration and treatment time. Among disinfectants tested in this study, 3% cresol, 0.2% sodium hypochlorite and 0.02% sodium hypochlorite delayed but not inactivated the embryonation of decorticated eggs at 3 weeks of incubation, because at 6 weeks of incubation, undeveloped eggs completed embryonation regardless of exposure time, except for 10% povidone iodine. When the albumin layer of A. suum eggs remained intact, however, even the 10% povidone iodine solution took at least 5 min to reasonably inactivate most eggs, but never completely kill them with even 60 min of exposure. This study demonstrated that the treatment of A. suum eggs with many commercially available disinfectants does not affect the embryonation. Although some disinfectants may delay or stop the embryonation of A. suum eggs, they can hardly kill them completely.
REFERENCE:
Oh KS, et al. Effects of Disinfectants on Larval Development of Ascaris suum Eggs. Korean J Parasitol. 2016 Feb;54(1):103-7. doi: 10.3347/kjp.2016.54.1.103. Epub 2016 Feb 26.

-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

viernes, 18 de marzo de 2016

Microbial Contamination on Used Surgical Masks

Objective: To assess the relationship of bacterial and fungal contamination on used surgical masks worn by the hospital personnel and microbial air quality in their working wards.
Methods: This is a cross-sectional study of 230 used surgical masks collected from 214 hospital personnel, and 215 indoor air samples collected from their working wards to culture for bacterial and fungal counts. This study was carried out at the hospital in Bangkok. Group or genus of isolated bacteria and fungi were preliminarily identified by Gram’s stain and lacto-phenol cotton blue. Data were analyzed using paired t-test and Pearson’s correlation coefficient at the significant level of p<0.050.
Results: Means and standard deviation of bacterial and fungal contamination on inside area of the used masks were 47 ± 56 and 15 ± 9 cfu/ml/piece, and on outside area were 166 ± 199 and 34 ± 18 cfu/ml/piece, respectively, p<0.001. The bacterial and fungal contamination on used masks from hospital personnel working in the male and female medical wards and out-patient department, as well as the bacterial and fungal counts of the indoor air sample collected from the same area were relatively higher than the other wards. The predominant isolated bacteria and fungi contaminated on inside and outside areas of the used masks and air samples were similar (Staphylococcus spp. and Aspergillus spp.; respectively). For its relationship, results found that bacterial and fungal counts in air samples showed significantly positive correlation with the bacterial contamination load on outside area of the used masks, r=0.16, p=0.018 and r=0.21, p=0.003, respectively.
Conclusion: High bacterial contamination on outside area of the used masks was demonstrated, and it showed a significant correlation with microbial air quality of working wards.

REFERENCE:
Luksamijarulkul, P et al. “Microbial Contamination on Used Surgical Masks among Hospital Personnel and Microbial Air Quality in Their Working Wards: A Hospital in Bangkok.” Oman Medical Journal 29.5 (2014): 346–350. PMC. Web. 18 Mar. 2016.
-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter

miércoles, 16 de marzo de 2016

Cursos para el 8º Simposio de Bioseguridad #SIBB16



Inscripciones:http://amexbio.wildapricot.org/Inscripciones
Posted by Asociación Mexicana de Bioseguridad A.C. (AMEXBIO) on miércoles, 16 de marzo de 2016

-----------------------------------------------------------
Sigue este Blog en Facebook y Twitter


LinkWithin

Related Posts Plugin for WordPress, Blogger...