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miércoles, 16 de julio de 2014

Monitoring #SelectAgent Theft, Loss and Release Reports in USA

cdc.gov
The APHIS/CDC Form 3, Report of Theft, Loss or Release of Select Agents and Toxins (TLR incident report) is the mechanism by which the theft, loss or release of a biological select agent and toxin (BSAT) is reported to the United States Department of Agriculture (USDA)/Animal and Plant Health Inspection Service (APHIS) or Health and Human Services (HHS)/ Center for Disease Control and Prevention (CDC). A total of seven hundred and twenty seven (727) TLR Incident Reports were received by CDC between 2004 and 2010.

REFERENCES:
Henkel RD, et al. Monitoring Select Agent Theft, Loss and Release Reports in the United States—2004-2010. Applied Biosafety Vol. 17, No. 4, 2012:171-180.
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lunes, 14 de julio de 2014

#LIBRO: Special Immunizations Program

The U.S. Army's Special Immunizations Program is an important component of an overall biosafety program for laboratory workers at risk of exposure to hazardous pathogens. The program provides immunizations to scientists, laboratory technicians and other support staff who work with certain hazardous pathogens and toxins. Although first established to serve military personnel, the program was expanded through a cost-sharing agreement in 2004 to include other government and civilian workers, reflecting the expansion in biodefense research in recent years. Protecting the Frontline in Biodefense Research examines issues related to the expansion of the Special Immunizations Program, considering the regulatory frameworks under which the vaccines are administered, how additional vaccines might be considered for inclusion in the Program, and factors that might influence the development and manufacturing of vaccines for the Special Immunizations Program.
REFERENCE:
National Research Council. Protecting the Frontline in Biodefense Research: The Special Immunizations Program. Washington, DC: The National Academies Press, 2011.
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jueves, 10 de julio de 2014

Comparison and analysis of biological agent category lists

the-scientist.com
Biological agents pose a serious threat to human health, economic development, social stability and even national security. The classification of biological agents is a basic requirement for both biosafety and biodefense. We compared and analyzed the Biological Agent Laboratory Biosafety Category list and the defining criteria according to the World Health Organization (WHO), the National Institutes of Health (NIH), the European Union (EU) and China. We also compared and analyzed the Biological Agent Biodefense Category list and the defining criteria according to the Centers for Disease Control and Prevention (CDC) of the United States, the EU and Russia. The results show some inconsistencies among or between the two types of category lists and criteria. We suggest that the classification of biological agents based on laboratory biosafety should reduce the number of inconsistencies and contradictions. Developing countries should also produce lists of biological agents to direct their development of biodefense capabilities.To develop a suitable biological agent list should also strengthen international collaboration and cooperation.
REFERENCE:
Tian D, Zheng T. Comparison and analysis of biological agent category lists based on biosafety and biodefense. PLoS One. 2014 Jun 30;9(6):e101163.
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jueves, 26 de junio de 2014

El virus de #Chikungunya

La fiebre chikungunya es una enfermedad vírica transmitida al ser humano por mosquitos infectados. Además de fiebre y fuertes dolores articulares, produce otros síntomas, tales como dolores musculares, dolores de cabeza, náuseas, cansancio y erupciones cutáneas. Algunos signos clínicos de esta enfermedad son iguales a los del dengue, con el que se puede confundir en zonas donde este es frecuente. Como no tiene tratamiento curativo, el tratamiento se centra en el alivio de los síntomas. Un factor de riesgo importante es la proximidad de las viviendas a lugares de cría de los mosquitos.  A partir de 2004 la fiebre chikungunya ha alcanzado proporciones epidémicas, y es causa de considerables sufrimientos y morbilidad. La enfermedad se da en África, Asia y el subcontinente indio. En los últimos decenios los vectores de la enfermedad se han propagado a Europa y las Américas. En 2007 se notificó por vez primera la transmisión de la enfermedad en Europa, en un brote localizado en el nordeste de Italia.
En México, se ha reportado el primer caso en Junio de 2014.
REFERENCIAS:
  1. Hoja informativa OMS sobre el virus chikungunya
  2. Hoja informativa OPS sobre el virus chikungunya
  3. Hoja de seguridad del virus de #Chikungunya
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lunes, 23 de junio de 2014

Efficacy of surface #disinfectant against gram-negative #bacteria

ABSTRACT (partial).
Background. We determined the efficacy of several SDCs against clinically relevant bacterial species with and without common types of multidrug resistance.
Methods. Bacteria species used were ATCC strains; clinical isolates classified as antibiotic-susceptible; and multi-resistant clinical isolates. The five evaluated SDCs were based on alcohol and an amphoteric substance (AAS), an oxygen-releaser (OR), surface-active substances (SAS), or surface-active-substances plus aldehydes (SASA; two formulations). Bactericidal concentrations of SDCs were determined at two different contact times. Efficacy was defined as a log10 ≥ 5 reduction in bacterial cell count.
Results. SDCs based on AAS, OR, and SAS were effective against all six species irrespective of the degree of multi-resistance. The SASA formulations were effective against the bacteria irrespective of degree of multi-resistance except for one of the four P. aeruginosa isolates (VIM-1). We found no general correlation between SDC efficacy and degree of antibiotic resistance.
Conclusions. SDCs were generally effective against gram-negative bacteria with and without multidrug resistance. SDCs are therefore suitable for surface disinfection in the immediate proximity of patients. Single bacterial isolates, however, might have reduced susceptibility to selected biocidal agents.

REFERENCE:
Reichel M et al. Efficacy of surface disinfectant cleaners against emerging highly resistant gram-negative bacteria. BMC Infect Dis. 2014; 14: 292.
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lunes, 16 de junio de 2014

Placing Global #Biosecurity Engagement Programs under the Umbrella of Global Health Security

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Global biosecurity engagement programs designed to prevent misuse of biological agents and pathogens internationally have increased dramatically under the National Strategy for Countering  Biological Threats (NSCBT), which outlined the commitment of the United States Government towards advancing health security.
But it is difficult to measure the effectiveness of these programs in improving biosecurity given that there have been relatively few attempts to misuse the life sciences. Current metrics that focus on outputs (what was done) as opposed to outcomes (the impact of what was done) have not been helpful in determining how these efforts might be improved in the future. With these metrics in mind, the goals of the programs have traditionally been more quantitative in nature – for example, increasing the number of agents secured and number of scientists engaged. Broadening the scope of biosecurity engagement metrics can help align program goals with a more qualitative approach that prioritizes the international partner’s global health security. Such an approach will be more efficient and successful in improving global and U.S. national biosecurity.
Rozo M. 2014 Placing Global Biosecurity Engagement Programs under the Umbrella of Global Health Security. Federation of American Scientists (FAS).
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miércoles, 11 de junio de 2014

#LIBRO: Conceptos Básicos del Control de Infecciones 2011, ahora en Español!

Esta nueva edición de Conceptos básicos de control de infecciones de IFIC, se elaboró sobre la base de las versiones anteriores. Con un enfoque científico, profundiza y actualiza los conocimientos necesarios para sostener el desarrollo de políticas y procedimientos locales. Este libro está enfocado a las áreas hospitalarias.
Un panel internacional de expertos revisó y actualizó la mayoría de los capítulos. Además se incorporaron secciones nuevas, con el fin de asegurar que esta edición ofrecería un completo y sólido caudal de conocimientos.
REFERENCE:
IFIC’s Basic Concepts of Infection Control, 2nd Edition, 2011

PDF Download:
Español. Descarga 1             Español. Descarga 2
English1                               English2
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jueves, 29 de mayo de 2014

Conferencias sobre Biotecnología y Derecho

La ciencia y la tecnología avanzan vertiginosamente. El derecho no es indiferente a ese progreso. Temas como la modificación genética y la biotecnología deben ser analizados cuidadosamente, no sólo desde el punto de vista legal, sino también científico. Por esa razón, es importante conocer a través de especialistas los conceptos básicos que nos permitan entender el fenómeno. En tal sentido, con el ánimo de contribuir a la actualización de los miembros del Poder Judicial de la Federación y de quienes aspiran pertenecer a él, en temas de novedad e importancia significativa, se delineó el presente Ciclo de Conferencias
sobre Biotecnología y Derecho.
Al finalizar el ciclo de conferencias, el alumno:
1. Distinguirá en qué consisten los organismos genéticamente modificados.
2. Conocerá el marco jurídico aplicable en materia de bioseguridad y organismos genéticamente modificados.
3. Contará con un panorama general sobre Biotecnología e innovación científica.
Dirigido al público en general interesado en el tema.
CONVOCATORIA    -    REGISTRO

INVITA:
Instituto de la Judicatura Federal 
Escuela Judicial

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