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viernes, 21 de diciembre de 2012

Infección ocupacional adquirida de Leishmaniasis cutánea,

Artículo completo
Abstract: En éste artículo se reportan dos casos de Leishmaniasis cutánea americana: Una autoinoculación con aguja contaminada durante el manejo de muestras, y una adquirida durante el trabajo de campo sobre biología de aves.

We report two occupationally acquired cases of American cutaneous leishmaniasis (ACL): one accidental laboratory autoinoculation by contaminated needlestick while handling an ACL lesion sample, and one acquired during field studies on bird biology. Polymerase chain reaction (PCR) assays of patient lesions were positive for Leishmania, subgenus Viannia. One isolate was obtained by culture (from patient 2 biopsy samples) and characterized as Leishmania (Viannia) naiffi through an indirect immunofluorescence assay (IFA) with species-specific monoclonal antibodies (mAbs) and by multilocus enzyme electrophoresis (MLEE). Patients were successfully treated with N-methyl-glucamine. These two cases highlight the potential risks of laboratory and field work and the need to comply with strict biosafety procedures in daily routines. The swab collection method, coupled with PCR detection, has greatly improved ACL laboratory diagnosis.

Felinto de Brito ME, et al. Occupationally acquired american cutaneous leishmaniasisCase Rep Dermatol Med. 2012;2012:279517. doi: 10.1155/2012/279517.
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