jueves, 19 de enero de 2017

Occupational HIV infection in a research laboratory

A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.

REFERENCE:
Soria A, Alteri C, Scarlatti G, et al. Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report. Clin Infect Dis. 2016 Dec 28.
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